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Thirteen actives. One reason they’re together.

The strongest formula isn’t the one with the most milligrams — it’s the one whose ingredients help each other. ProleevaMax is built on two kinds of synergy: actives that improve each other’s absorption, and actives that work across connected steps of the same response.

standardized actives
13

standardized actives

inflammatory pathways
6

inflammatory pathways

curcumin absorption, paired
20×

curcumin absorption, paired

The most important number isn’t on the label

An ingredient only works if you absorb it.

Curcumin is one of the most-studied anti-inflammatory botanicals — and one of the hardest to absorb. The fix is the oldest trick in the formula: a little black pepper.

Curcumin + Black Pepper (Piperine)

Curcumin is famously hard to absorb. Pairing it with piperine — the active in black pepper — slows its breakdown so far more reaches the bloodstream.

+2,000%curcumin bioavailability · 20×
Curcumin alone
With piperine20×
0relative absorption →20×
Read the study — Planta Medica, 1998

Beyond the obvious pairing

Curcumin and black pepper is the famous pair. It isn’t the only one.

Plenty of formulas copy the piperine trick. The synergy that sets ProleevaMax apart works a different axis entirely — the line between the gut and the brain.

A pairing that’s distinctly ours

L-Glutamine + L-Serine

Most formulas stop at curcumin and black pepper. ProleevaMax adds a second kind of synergy — two amino acids that work the gut–brain axis from both ends.

Gut-barrier integrity

L-Glutamine

Helps keep the gut lining intact. A leaky barrier quietly feeds inflammation throughout the body — and the gut is wired directly to the brain.

Read the full ingredient page

Nervous-system resilience

L-Serine

Supports the structure of the nervous system itself, so chronic inflammation has less chance to wear it down over time.

Read the full ingredient page

Together they work along the gut–brain axis — supporting the barrier on one end and the nervous system on the other. It’s a neuroinflammation angle that single-ingredient formulas rarely reach.

The synergy network

One formula, wired across six pathways.

Chronic inflammation rarely runs through a single point — so a single ingredient can only ever reach part of it. ProleevaMax routes thirteen standardized actives across all six pathways of the response at once.

Most supplements

One ingredient. One target.

A single active acts at a single point of a response that runs through many.

ProleevaMax

13 actives. 6 pathways.

Each standardized active routed to one of six connected pathways — a system, not a dose.

012 activesInflammatory Signaling022 activesAntioxidant Defense032 activesAbsorption & Delivery045 activesNervous System Resilience051 activeGut Barrier Integrity061 activeAdaptive Energy13actives
01Inflammatory Signaling
CurcuminBoswellia Serrata
02Antioxidant Defense
ResveratrolMatcha Green Tea (EGCG)
03Absorption & Delivery
Black Pepper Extract (Piperine)L-Arginine HCl
04Nervous System Resilience
L-SerineCholine L-BitartrateGABA5-HTP (Griffonia seed)Vitamin B6 (Pyridoxine HCl)
05Gut Barrier Integrity
L-Glutamine
06Adaptive Energy
Asian Ginseng Root (Panax Ginseng)

Synergy, explained

Common questions.

Curcumin on its own is poorly absorbed — most of a dose passes through without reaching the bloodstream. Piperine, the active compound in black pepper, slows curcumin’s breakdown in the gut and liver. In a human pharmacokinetic study, co-administering piperine raised curcumin bioavailability by up to 2,000% (about 20-fold), which is why the two are paired in the formula.

References

The science behind the pairing.

The bioavailability figure traces to a peer-reviewed human study. Each links to the source.

  1. 1.Shoba G, et al.. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica. 1998. https://doi.org/10.1055/s-2006-957450
  2. 2.Tripathi AK, et al.. Piperine: pharmacological aspects and its therapeutic potential. Beni-Suef University Journal of Basic and Applied Sciences. 2022. https://doi.org/10.1186/s43088-022-00196-1

† From a human pharmacokinetic study on curcumin co-administered with piperine (Shoba et al., 1998). Describes ingredient absorption, not a ProleevaMax outcome. The synergy described here explains how the formula is designed; it is not a claim that ProleevaMax produces a specific result. These statements have not been evaluated by the Food and Drug Administration.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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